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. 2022 Apr 7;59(4):2100769. doi: 10.1183/13993003.00769-2021

TABLE 4.

Relative risk of severe outcomes of severe acute respiratory syndrome coronavirus 2 infection in patients exposed to glucocorticoids, by cumulative prednisolone-equivalent dose <2000 mg (moderate) or ≥2000 mg (high)

Outcome Dose Events Relative risk (95% CI)
Exposed Unexposed Crude Adjusted
Hospital admission Moderate 38 (n=69) 3373 (n=36 200) 5.91 (4.76–7.33) 1.20 (0.89–1.62)
High 45 (n=67) 3373 (n=36 200) 7.21 (6.08–8.55) 1.47 (1.15–1.89)
ICU admission Moderate 5 (n=69) 400 (n=36 200) 6.56 (2.80–15.34) 1.92 (0.83–4.46)
High 5 (n=67) 400 (n=36 200) 6.75 (2.89–15.78) 1.60 (0.62–4.14)
Death Moderate 18 (n=69) 658 (n=36 200) 14.35 (9.58–21.50) 1.83 (1.08–3.11)
High 24 (n=67) 658 (n=36 200) 19.71 (14.18–27.39) 2.96 (2.00–4.37)

ICU: intensive care unit.