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. 2021 Aug 30;12:718548. doi: 10.3389/fimmu.2021.718548

Table 3.

G3BP promotes viral replication.

Genome Virus Mechanism of Action References
dsDNA VV G3BP1,Caprin-1 is recruited to the viral plant and enhances the transcription of VV (85)
dsRNA IBDV The overexpression of G3BP1 enhances SGs formation and promotes viral replication (86)
(+)ssRNA CHIKV G3BP1/2 regulates the conversion of viral genome to negative strand synthesis (87)
SFV G3BP1 binds to nsP3 protein and 40S ribosomal subunit to promote efficient translation of viral mRNA (24)
EEEVVEEV FXR interacts with G3BP1/2 and nsP3 proteins to assemble the viral replication complex (vRC) (88)
HCV G3BP1 acts as a component of the replication complex to control the replication of HCV (89)
DENV2 SfRNA interacts with G3BP1, G3BP2, Caprin1 and regulates the translation of ISGs mRNA (90, 91)
RUBV G3BP co-localizes with viral ssRNA and participates in the role of viral replication (92)
NDV G3BP1 regulates NDV replication through controlling the translation (93)
ZIKV Virus interacts with G3BP1 to impair the assembly of SGs (94)
(-) ssRNA RSV SG is produced during RSV infection to enhance replication (95)