Table 3.
G3BP promotes viral replication.
Genome | Virus | Mechanism of Action | References |
---|---|---|---|
dsDNA | VV | G3BP1,Caprin-1 is recruited to the viral plant and enhances the transcription of VV | (85) |
dsRNA | IBDV | The overexpression of G3BP1 enhances SGs formation and promotes viral replication | (86) |
(+)ssRNA | CHIKV | G3BP1/2 regulates the conversion of viral genome to negative strand synthesis | (87) |
SFV | G3BP1 binds to nsP3 protein and 40S ribosomal subunit to promote efficient translation of viral mRNA | (24) | |
EEEVVEEV | FXR interacts with G3BP1/2 and nsP3 proteins to assemble the viral replication complex (vRC) | (88) | |
HCV | G3BP1 acts as a component of the replication complex to control the replication of HCV | (89) | |
DENV2 | SfRNA interacts with G3BP1, G3BP2, Caprin1 and regulates the translation of ISGs mRNA | (90, 91) | |
RUBV | G3BP co-localizes with viral ssRNA and participates in the role of viral replication | (92) | |
NDV | G3BP1 regulates NDV replication through controlling the translation | (93) | |
ZIKV | Virus interacts with G3BP1 to impair the assembly of SGs | (94) | |
(-) ssRNA | RSV | SG is produced during RSV infection to enhance replication | (95) |