FIGURE 2.

Changes in the pulmonary pathology of mice with OVA-induced chronic asthma. Representative hematoxylin and eosin (H&E)-stained lung sections showing inflammatory cell infiltration around the small airways, bronchial wall thickening, and constriction (200×; the black arrows indicate the aggregation of inflammatory cells, and the black vertical line indicates the airway wall thickness). PAS staining indicating the mucus-producing goblet cells around the small airways (200×; similar to the purple area indicated by the black arrow). Masson’s trichome staining indicating collagen fiber deposition around small airways (200×; similar to the blue area indicated by the black arrow).