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. 2021 Aug 30;12:723152. doi: 10.3389/fmicb.2021.723152

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Copyright © 2021 Zheng, Wu, Zou, Wang, He and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metagenomic functional prediction of the respiratory microbiota using PICRUSt. Bacterial metagenomic functional categories were derived from level 3 KEGG pathways. Gene functions with a significant difference (corrected P value < 0.05) and parts of the pathways associated with asthma are shown. (A) Control group vs OVA1W group in URT samples. (B) Control group vs OVA2W group in URT samples. (C) Control group vs OVA6W group in URT samples. (D) OVA1W group vs OVA6W group in URT samples. (E) OVA2W group vs OVA6W group in URT samples. (F) Control group vs OVA1W group in LRT samples. (G) Control group vs OVA2W group in LRT samples. (H) Control group vs OVA6W group in LRT samples. (I) OVA1W group vs OVA6W group in LRT samples. (J) OVA2W group vs OVA6W group in LRT samples.