. 2021 Sep 9;70:102831. doi: 10.1016/j.amsu.2021.102831

Table 1.

Summary of search results.

Author/date of publication/journal/country	Study type and level of evidence	Patient group	Outcomes follow up	Key results	Additional comments
Lederle F A et al., 2019, N Eng J Med, USA [2]. OVER	Randomized control trial- Level 1b	Total of 881 patients with AAA * Group 1 EVAR: 444 Group 2 OSR: 437 Follow-up, 14.2 years. *Median was 9.4 years	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all cause and aneurysm related mortality	Group 1 EVAR: 1.6% (7) patients. Group 2 OSR: 0.2%% (1) patients. 95% confidence interval = 0.1–2.6. P value = 0.03 *Statistically significant	Long term Multi Center *Specific skills and device training for the investigators.
Van Schaik et al., 2017, JVS, Netherland [3] Dream	Randomized controlled trial -level 1b	Total of 351 patients with AAA Group 1 EVAR: 173 Group 2 OSR: 178 Follow-up was 12 years. * Median was 10.2 years.	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all-cause, and aneurysm related mortality	Group 1 EVAR: 4 (2.3%). Group 2 OSR: 0 P-value <0.05 Statistically Significant	* Long term follow up Multicenter Lack of Blinding. *Old devices used
Rajesh Patel et al., 2016, Lancet, UK [4]. EVAR-1	Randomized control trial- Level 1b	Total of 1252 patients with AAA Group 1 EVAR: 626 Group 2 OSR: 626 Follow-up was 15·8 years. *Median was 12.4 years.	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all-cause, and aneurysm related mortality	Group 1 EVAR: 31 (5%) Patients. Group 2 OSR: 5 (0.8%) Patients. 95% confidence interval 2.50–16.75 P-value < 0.05 *Statistically significant	* Long term Multi Centre Old devices used * Imaging was of low quality *Follow up changed from CT to Ultrasound .
Huang et al., 2015, JVS, USA [5].	Retrospective Cohort -Level 2a	Total of 1116 patients with AAA Group 1 OSR: 558 Group 2 EVAR: 558 Follow-up, 10 years; *Median was 7.6 years.	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all cause and aneurysm related mortality	Group 1 OSR: 0.17% (1) Patients Group 2 EVAR: 1.4% (8) Patients; * 95% confidence interval = ;1.01–64.99 P value = 0.05 Statistically significant	Large sample size Retrospective *OSR group are less rigorously followed up.
Kristina A Giles et al., 2011, JVS, USA [6].	Retrospective Cohort -Level 2a	Total of Patients with AAA Group 1 EVAR: 22.826 Group 2 OSR: 22.826 Follow Up 6 years. Median was	*Endpoint is re-interventions and Secondary Ruptures	Group 1 EVAR: 441(19.3%) RR 0.50 Group 2 OSR: 76(3.3%) RR 0.09 95% Confidence Interval = 2.97–4.50 P value < 0.001 * Statistically Significant	Large Sample Size Longitudinal design *Lack of clinical details

Author/date of publication/journal/country	Study type and level of evidence	Patient group	Outcomes follow up	Key results	Additional comments
Lederle F A et al., 2019, N Eng J Med, USA [2]. OVER	Randomized control trial- Level 1b	Total of 881 patients with AAA * Group 1 EVAR: 444 Group 2 OSR: 437 Follow-up, 14.2 years. *Median was 9.4 years	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all cause and aneurysm related mortality	Group 1 EVAR: 1.6% (7) patients. Group 2 OSR: 0.2%% (1) patients. 95% confidence interval = 0.1–2.6. P value = 0.03 *Statistically significant	Long term Multi Center *Specific skills and device training for the investigators.
Van Schaik et al., 2017, JVS, Netherland [3] Dream	Randomized controlled trial -level 1b	Total of 351 patients with AAA Group 1 EVAR: 173 Group 2 OSR: 178 Follow-up was 12 years. * Median was 10.2 years.	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all-cause, and aneurysm related mortality	Group 1 EVAR: 4 (2.3%). Group 2 OSR: 0 P-value <0.05 Statistically Significant	* Long term follow up Multicenter Lack of Blinding. *Old devices used
Rajesh Patel et al., 2016, Lancet, UK [4]. EVAR-1	Randomized control trial- Level 1b	Total of 1252 patients with AAA Group 1 EVAR: 626 Group 2 OSR: 626 Follow-up was 15·8 years. *Median was 12.4 years.	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all-cause, and aneurysm related mortality	Group 1 EVAR: 31 (5%) Patients. Group 2 OSR: 5 (0.8%) Patients. 95% confidence interval 2.50–16.75 P-value < 0.05 *Statistically significant	* Long term Multi Centre Old devices used * Imaging was of low quality *Follow up changed from CT to Ultrasound .
Huang et al., 2015, JVS, USA [5].	Retrospective Cohort -Level 2a	Total of 1116 patients with AAA Group 1 OSR: 558 Group 2 EVAR: 558 Follow-up, 10 years; *Median was 7.6 years.	Endpoint is Secondary Ruptures. Other outcomes: re-interventions, all cause and aneurysm related mortality	Group 1 OSR: 0.17% (1) Patients Group 2 EVAR: 1.4% (8) Patients; * 95% confidence interval = ;1.01–64.99 P value = 0.05 Statistically significant	Large sample size Retrospective *OSR group are less rigorously followed up.
Kristina A Giles et al., 2011, JVS, USA [6].	Retrospective Cohort -Level 2a	Total of Patients with AAA Group 1 EVAR: 22.826 Group 2 OSR: 22.826 Follow Up 6 years. Median was	*Endpoint is re-interventions and Secondary Ruptures	Group 1 EVAR: 441(19.3%) RR 0.50 Group 2 OSR: 76(3.3%) RR 0.09 95% Confidence Interval = 2.97–4.50 P value < 0.001 * Statistically Significant	Large Sample Size Longitudinal design *Lack of clinical details