Fig. 10.

RNA expression levels after 1 week of implantation determined utilizing Bulk-RNA-Seq and RT-PCR. a) The 2D PCA of RNA expression profile in PFC/PCL and PFC/PCL-BA, respectively; b) Heatmap representing the expression of angiogenesis-related regulators; c) Detection of gene expression of key angiogenesis-related regulators (Pecam1 and Vegfa) by RT-PCR; d) Heatmap representing the expression of positive and negative regulators of osteoclast differentiation; e) Detection of gene expression of osteoclast differentiation-related regulators (Tnfrsf11a and Ocstamp) by RT-PCR.