Figure 6.

ANE treatment has no significant tumorigenicity effect in immune competent mice. A. Representative 18F-FDG-PET scaning imaging of whole mice by different sections. Blue/red circles indicate the liver region. H: heart; B: bladder. B. Representative hematoxylin & eosin (H&E) stained images of liver tissues from mice following long-term low-dose ANE treatment. Scale bar: 100 µm. C. Statistic bar graph of standarized-uptake-value (SUV) from A. p value was calculated by unpaired t test. Experiments were performed in three biological replicates and presented as mean ± standard errors. Mice number are 8 and 7 in mock and ANE group, respectively.