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. 2021 Aug 27;18(15):3581–3587. doi: 10.7150/ijms.63603

Figure 1.

Figure 1

Clinical manifestation of normal premature infants and those with retinopathy of prematurity who require treatment. (A) Fundoscopy of a premature infant in the control group; (B) Fundoscopy of aggressive posterior ROP: the retina is only vascularized within Zone 1, with apparent tortuosity of retinal arteries and dilation of veins (plus disease); (C) Fundoscopy of stage 3 ROP with plus disease in posterior Zone 2; (D) Fundus fluorescein of ROP, in which prominent retinal neovascularization, plus disease and dragged disc are noted.