Table 3.
Univariate and multivariate cox regression analyses of disease-free survival.
| Characteristic | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | ||||
| Sex, male vs. female | 1.111(0.854-1.395) | 0.454 | |||||
| Age≥60, year | 1.232(0.912-1.601) | 0.412 | |||||
| HBsAg, positive | 1.214(0.854-1.652) | 0.254 | |||||
| AFP, ≥20 ng/ml | 2.456(1.598-3.384) | 0.112 | |||||
| Tumor number, multiple vs. single | 1.119(0.612-2.531) | 0.154 | |||||
| Tumor size, ≥5 cm | 2.945(1.754-3.845) | 0.001 | 2.754(1.564-3.564) | 0.012 | |||
| Satellite nodules, yes | 1.654(0.954-2.018) | 0.111 | |||||
| Lymph node invasion, yes | 1.335(0.789-2.017) | 0.385 | |||||
| Microvascular invasion, positive | 2.151(1.433-3.011) | <0.001 | 2.012(1.398-2.874) | 0.002 | |||
| PRMT4 expression, high | 2.549(1.798-3.987) | 0.001 | 2.124(1.654-3.812) | 0.006 | |||
Abbreviation: HBsAg: Hepatitis B surface antigen; AFP: α -fetoprotein. Bold denotes P-value <0.05