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. 2021 Sep 2;24(5):758. doi: 10.3892/mmr.2021.12398

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Copyright: © Yuan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effect of miR-29a-modified hADSCs-exo on the proliferation and migration of HSFBs. (A) Proliferation of HSFBs treated with different hADSCs-exo. (B) Effect of miR-29a-modified hADSCs-exo on the scratch healing of HSFBs (magnification, ×10). Two-way ANOVA followed by Bonferroni post hoc test was used to compare the differences among different groups. *P<0.05, ***P<0.001, ****P<0.0001 vs. NC at the same time point; ^##P<0.01, ^####P<0.0001 vs. inhibitor-exo group at the same time point. NC, negative control; mimics-exo, exosomes from miR-29a overexpressed hADSCs treated group; inhibitor-exo, exosomes from miR-29a knockdown hADSCs treated group; miR, microRNA; hADSCs, human adipose-derived mesenchymal stem cells; HSFBs, human hypertrophic scar fibroblasts.