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. 2021 Aug 26;64(17):12603–12629. doi: 10.1021/acs.jmedchem.1c00497

Scheme 1. Reagents and Conditions: (a) K2CO3, EtOH, 80 °C, 2–6 h; (b) mCPBA, Dichloromethane (DCM), rt, 1 h then 35 °C, 12 h (c) 1 M HCl in EtOAC, rt, 12 h; (d) K2CO3, MeCN, KI, 60 °C, 24 h.

Scheme 1