. 2021 Aug 26;64(17):12603–12629. doi: 10.1021/acs.jmedchem.1c00497

Table 1. Structure and Binding Affinities for 5-HT_2A, 5-HT₆, 5-HT₇, and D₂ Receptors of Compounds 2–12 (Series I) and Reference Drugs^a.

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Binding affinity values are represented as pK_i (i.e., −log K_i) and expressed as mean ± standard error of the mean (SEM) from at least three experiments performed in duplicate.

Table 1. Structure and Binding Affinities for 5-HT2A, 5-HT6, 5-HT7, and D2 Receptors of Compounds 2–12 (Series I) and Reference Drugsa.

Table 1. Structure and Binding Affinities for 5-HT_2A, 5-HT₆, 5-HT₇, and D₂ Receptors of Compounds 2–12 (Series I) and Reference Drugs^a.