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RAPA partially reverses LBP-induced inhibition of autophagy in I/R-induced H9C2 cells. (A) Western blotting results of the protein expression levels of (B) Beclin 1, (C) LC3-II/LC3-I and (D) P62 in I/R-induced H9C2 cells with the treatment of LBP (15 µg/ml) and RAPA in combination or alone, with GAPDH serving as an endogenous reference. ***P<0.001 vs. I/R; ^^^P<0.001 vs. LBP-15; ###P<0.001 vs. RAPA. I/R, ischemia/reperfusion; RAPA, rapamycin; LBP, Lycium barbarum polysaccharide.
