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. 2021 Aug 20;12(9):1421–1426. doi: 10.1021/acsmedchemlett.1c00216

Table 4. In Vivo PK Profile of Compound 15f, Dosing to SCID Mice Using SSV.

dosage (oral) 50 mg/kg 100 mg/kg
T1/2 (h) 2.9 2.4
Cmax (μg/L) 13 067 27 800
Tmax (h) 1.33 1.67
AUC0–t (μg·h/L) 82 209 162 617