Table 1.
Patient Characteristics According to the Presence of Venous Thromboembolism (VTE)
| Characteristics | ICH without VTE (n=779) | ICH with VTE (n=69) | P-value |
|---|---|---|---|
| Demographics | |||
| Male | 433 (55.60) | 41 (59.40) | 0.538 |
| Age (year) | 68.03 (55.89–79.25) | 69.53 (60.64–80.36) | 0.205 |
| Age > 60 years | 517 (66.40) | 54 (78.30) | 0.043* |
| Comorbidities | |||
| Hypertension | 577 (74.10) | 46 (66.70) | 0.182 |
| Hyperlipidemia | 211 (27.10) | 19 (27.50) | 0.936 |
| Diabetes | 170 (21.80) | 17 (24.60) | 0.589 |
| Congestive heart failure | 24 (3.10) | 6 (8.70) | 0.029* |
| Atrial fibrillation | 180 (23.10) | 21 (30.40) | 0.170 |
| COPD | 4 (0.50) | 0 | 1.000 |
| Respiratory failure | 243 (31.20) | 35 (50.70) | 0.001* |
| Chronic kidney injury (48 h) | 245 (31.50) | 22 (31.90) | 0.941 |
| Malignancy | 101 (13.00) | 22 (31.90) | 0.000* |
| ARDS | 17 (2.20) | 4 (5.80) | 0.084 |
| Pneumonia | 217 (27.90) | 18 (26.10) | 0.753 |
| Pulmonary circulation disease | 8 (1.0) | 13 (18.80) | 0.000* |
| Renal failure | 56 (7.20) | 10 (14.50) | 0.030* |
| Liver failure | 31 (4.00) | 2 (2.90) | 1.000 |
| Hypothyroidism | 57 (7.30) | 5 (7.20) | 0.983 |
| Rheumatoid arthritis | 16(2.10) | 0 | 0.633 |
| Coagulopathy | 60 (7.70) | 14 (20.30) | 0.000* |
| Deficiency anemia | 94 (2.10) | 8 (11.60) | 0.908 |
| Electrolyte disturbances | 209 (26.80) | 28 (40.60) | 0.015* |
| Hospitalization time > 16 days | 211 (27.10) | 33 (47.80) | 0.000* |
| ICU (day) | 4.89(2.90–9.92) | 5.92(3.36–11.63) | 0.920 |
| SOFA | 3.0(2.0–5.0) | 3.0(2.0–5.0) | 0.139 |
| LODS | 3.0 (2.0–5.0) | 4.0 (2.0–6.0) | 0.050* |
| GCS | 14.0 (10.0–15.0) | 14.0 (8.0–15.0) | 0.763 |
| MELD | 9.0 (7.0–14.0) | 11.0 (7.0–18.0) | 0.039* |
| MELD-initial | 9.0 (7.0–13.0) | 11.0 (7.0–17.0) | 0.037* |
| Mechanical ventilation | 536 (68.80) | 52 (75.40) | 0.258 |
| Mechanical ventilation time (hours) | 135.21 (45.00–135.21) | 135.21 (50.25–175.02) | 0.183 |
| PT-min | 12.80 (12.20–13.60) | 13.10 (12.30–14.00) | 0.187 |
| PT-max | 13.40 (12.70–15.10) | 14.70 (13.00–17.95) | 0.001* |
| INR-min | 1.10 (1.00–1.20) | 1.10 (1.00–1.30) | 0.161 |
| INR-max | 1.20 (1.10–1.40) | 1.30 (1.10–1.80) | 0.003* |
| APTT-min | 25.20 (23.20–27.70) | 26.10 (23.95–28.45) | 0.071 |
| APTT-max | 27.30 (24.60–31.10) | 30.50 (26.55–35.75) | 0.000* |
Note: Values are expressed as median (interquartile range) or number (percent). *Indicates P < 0.05.
Abbreviations: COPD, chronic obstructive pulmonary disease; ARDS, acute respiratory distress syndrome; SOFA, sequential organ failure score; LODS, logistic organ dysfunction score; GCS, Glasgow coma scale; MELD, model for end-stage liver disease; IQR, interquartile range; PT, prothrombin time; INR, international normalized ratio; APTT, activated partial thromboplastin time; VTE, venous thromboembolism; ICH, intracerebral hemorrhage.