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. 2021 Sep 8;14:1093–1104. doi: 10.2147/JAA.S321332

Figure 3.

Figure 3

Relationship between relative glucocorticoid receptor binding affinity and the therapeutic index for various intranasal corticosteroids.12,32,34,35,38,62

Notes: The therapeutic index is defined here as the ratio of the dose that causes measurable systemic activity (defined as dose for cortisol suppression) divided by the therapeutic dose.

Abbreviations: BDP, beclomethasone dipropionate; BUD, budesonide; CIC, ciclesonide; DEX, dexamethasone; FF, fluticasone furoate; FLU, flunisolide; FP, fluticasone propionate; MF, mometasone furoate; TAA, triamcinolone acetonide.