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. 2021 Aug 12;74(10):1776–1785. doi: 10.1093/cid/ciab701

Table 4.

Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Transmission in the Household

Index or Household Risk Factor Susceptible Household Contacts Incident Secondary Cases Secondary Household Attack Rate (95% CI) Odds Ratio (95% CI) Adjusted Odds Ratio (95% CI)
Non-White 41 21 51% (33–69) 4.4 (1.5–13.0) 4.8 (1.5–15.4)
White, non-Hispanic 62 12 19% (10–35) -
Higher index nasopharyngeal viral loada - - - 3.5 (1.5–8.1) 3.6 (1.5–8.5)
High living densityb 29 15 52% (27–75) 3.3 (1.02–10.9) 1.4 (.4–4.6)
Not high living density 74 18 24% (15–37) -

Adjusted odds ratio adjusts for viral load as a continuous variable and race-ethnicity and living density as dichotomous variables.

Abbreviation: CI, confidence interval.

aOdds ratio for 3 log10 increase in the index viral load (VL). For example, the odds of transmission in a household where the index VL is 1 × 109 copies/mL is 3.5 times greater than in a household where the index VL is 1 × 106 copies/mL.

bDefined as more than 3 people occupying fewer than 6 rooms.