Table 3. Cytotoxicity Data for Human HUVECs and HepG2 Cells.
IC50 (μM)a |
||
---|---|---|
compound | HUVECs | HepG2 cells |
4 | 31.90 ± 6.56 | 12.85 ± 1.09 |
5 | 22.45 ± 5.18 | 10.78 ± 0.63 |
6 | 18.47 ± 1.13 | 9.78 ± 1.33 |
7 | 29.72 ± 9.35 | 13.04 ± 1.58 |
8 | 28.53 ± 4.56 | 12.44 ± 1.84 |
9 | 32.85 ± 6.51 | 14.81 ± 2.64 |
10 | 29.02 ± 4.95 | 12.19 ± 2.32 |
11 | 34.50 ± 3.10 | 13.28 ± 1.66 |
12 | % RA = 70 ± 1b | % RA = 52 ± 1b |
13 | % RA = 90 ± 2b | %RA = 31 ± 3b |
Means of three independent measurements ± SD.
Means ± SD for the residual cell viability at a 50 μM compound concentration from two independent experiments.