Table 3.

Biochemical parameters

	Standard of care (N = 31)	Alirocumab (N = 30)	P Value
LDL cholesterol, mmol/L
Baseline	3.18 ± 0.97	3.04 ± 0.78	–
After 36 weeks treatment	2.22 ± 0.69	1.32 ± 0.39	< 0.0001
Changes from baseline	−0.96 ± 0.59	−1.72 ± 0.51	< 0.0001
HDL cholesterol, mmol/L
Baseline	1.30 ± 0.41	1.41 ± 0.61	–
After 36 weeks treatment	1.38 ± 0.43	1.48 ± 0.47	0.35
Changes from baseline	0.08 ± 0.36	0.07 ± 0.38	0.74
Triglycerides, mmol/L
Baseline	1.56 (1.19 to 2.38)	1.84 (1.19 to 2.56)	–
After 36 weeks treatment	1.53 (1.09 to 2.26)	1.54 (1.00 to 2.09)	0.68
Changes from baseline	−0.05 (0.64 to 1.42)	−0.29 (− 0.96 to 0.35)	0.077
CRP, mg/L
Baseline	1.62 (0.90 to 3.00)	1.69 (0.75 to 3.37)	–
After 36 weeks treatment	1.10 (0.89 to 2.50)	1.59 (0.92 to 2.61)	0.64
Changes from baseline	0.54 (−0.46 to 1.34)	0.12 (−0.74 to 1.08)	0.50

CRP C-reactive protein, LDL low-density lipoprotein, HDL high-density lipoprotein