Table 1.
Demographic data of the study subjects
| Clinical features | Phase I | Phase II | Combined | |||
|---|---|---|---|---|---|---|
| sALS (n = 371) | Control (n = 711) | sALS (n = 300) | Control (n = 1076) | sALS (n = 671) | Control_2 (n = 1787) | |
| Sex, M/F (ratio) | 227/144 (1.58:1) | 283/428 (0.66:1) | 183/117 (1.56:1) | 453/623 (0.73:1) | 410/261 (1.57:1) | 736/1051 (0.70:1) |
| Age (year, mean ± SD) | 55.13 ± 10.28 | 69.41 ± 8.42 | 55.16 ± 9.82 | 69.83 ± 7.70 | 55.14 ± 9.97 | 69.66 ± 7.91 |
| Age at onset (year, mean ± SD) | 53.42 ± 10.28 | – | 53.49 ± 9.56 | – | 53.45 ± 9.96 | – |
| Site of onset, bulbar (%) | 73/371 (19.68%) | – | 59/300 (19.61) | – | 132/671 (19.67%) | – |
sALS, sporadic amyotrophic lateral sclerosis; AAO, age at onset