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. 2020 Sep 18;16(4):368–375. doi: 10.1159/000510061

Table 1.

Clinical characteristics of ER-positive patients with fulvestrant usage (n = 135)

Covariate level All patients (n = 135) Fulvestrant usage p value
first line (n = 116) ≥second line (n = 19)
Age at diagnosis, years 53 (27–82) 53 (27–82) 52 (30–71) 0.792
Age at fulvestrant usage, median years 57 (30–67) 57 (30–67) 55 (35–52) 0.620
ER, n (%)
 Negative 14 (10.37) 12 (10.34) 2 (10.5) 0.977
 Positive 121 (89.63) 104 (89.65) 17 (89.5)
PR, n (%)
 Negative 27 (20.00) 22 (18.97) 5 (26.32) 0.438
 Positive 108 (80.00) 94 (81.03) 14 (73.68)
HER2, n (%)
 Negative 108 (80.00) 91 (78.44) 17 (86.47) 0.538
 Positive 14 (10.37) 13 (11.20) 1 (5.26)
 Unknown 13 (9.63) 12 (9.48) 1 (5.26)
Histological grade, n (%)
 I 15 (11.11) 12 (10.34) 3 (15.79) 0.080
 II 68 (50.37) 56 (48.28) 12 (63.16)
 III 52 (38.52) 48 (41.38) 4 (21.05)
Stage, n (%)
 I 21 (15.55) 20 (17.44) 1 (5.26) 0.205
 II 49 (36.30) 39 (33.85) 10 (52.63)
 III 53 (39.26) 45 (38.79) 8 (42.11)
 IV 12 (8.89) 12 (10.34) 0 (0)
Metastatic sites, n (%)
 Lymph nodes 43 (31.85) 40 (34.88) 3 (15.79) 0.364
 Bone 80 (59.26) 68 (58.62) 12 (63.12)
 Visceral 69 (51.11) 62 (53.44) 7 (36.84)