Table 3.
Cox proportional hazard analysis of influence on progression-free survival
| Variables | Hazard ratio | 95% CI | p value |
|---|---|---|---|
| Age | |||
| <60 years | reference | ||
| ≥60 years | 0.990 | 0.423–2.371 | 0.982 |
| Tumor grade | |||
| I | reference | ||
| II | 1.700 | 0.474–6.097 | 0.415 |
| III | 2.179 | 0.798–5.000 | 0.066 |
| Tumor stage | |||
| I | reference | ||
| II | 1.660 | 0.162–17.013 | 0.669 |
| III | 1.045 | 0.110–9.903 | 0.969 |
| IV | 0.763 | 0.082–7.094 | 0.812 |
| ER status | |||
| Negative | reference | ||
| Positive | 0.372 | 0.066–2.095 | 0.262 |
| PR status | |||
| Negative | reference | ||
| Positive | 1.252 | 0.472–3.322 | 0.652 |
| HER2 status | |||
| Unknown | reference | ||
| Negative | 1.384 | 0.190–10.087 | 0.749 |
| Positive | 1.270 | 0.449–3.588 | 0.593 |
| DFS, months | |||
| ≤24 | reference | ||
| >24 | 0.488 | 0.209–1.142 | 0.098 |
| Metastatic sites | |||
| 1 | reference | ||
| ≥2 | 1.123 | 0.432–4.321 | 0.538 |
| Bone metastasis | |||
| No | reference | ||
| Yes | 1.244 | 0.455–3.403 | 0.670 |
| Visceral metastasis | |||
| No | reference | ||
| Yes | 1.454 | 0.494–4.279 | 0.497 |
| CT before | |||
| No | reference | ||
| Yes | 2.225 | 1.097–4.510 | 0.027 |