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Molecular mechanisms of lncRNAs. (A) LncRNAs modulate histone modification and chromatin remodeling. (B) LncRNAs serve as scaffolds for various proteins. (C) Nuclear lncRNAs participate in mRNA processing. (D) LncRNAs act as miRNA sponges or ceRNAs in regulating miRNAs. (E) LncRNAs regulate the stability and posttranslational modifications of some proteins. (F) lncRNAs stabilize mRNAs. (G) lncRNAs encode functional small peptides.
