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TRC have increased FAO and glycolysis. MCF7 cells and TRC were seeded on 96-well plates and pretreated with endoxifen (END, 5 µM), MK2206 (MK, 5 µM), etomoxir (ETO, 50 µM), END plus MK, or END plus ETO for 24 h and analyzed with the Agilent Seahorse XF Analyzer for ECAR and OCR. Average (six replicates) ECAR (mpH/min/20000 cells) and OCR (pMol/min/20000 cells) are presented with SD indicated. * indicates a significant difference (P < 0.05) between the NT and treated conditions.
