Table 3. Correlation analyses between ceruloplasmin and gene markers of various T cells in TIMER.
Description | Gene markers | BC | |||
None | Purity | ||||
Cor | P | Cor | P | ||
Th1 | TBX21 | 0.208 | *** | 0.103 | ** |
STAT4 STAT1 |
0.255 | *** | 0.164 | *** | |
0.19 | *** | 0.166 | *** | ||
IFNG | 0.209 | *** | 0.15 | *** | |
TNF | 0.262 | *** | 0.227 | *** | |
Th2 | GATA3 | 0.435 | *** | -0.402 | *** |
STAT6 | -0.056 | 0.065 | -0.106 | *** | |
STAT5A | 0.121 | *** | 0.051 | 0.11 | |
IL13 | 0.143 | *** | 0.107 | *** | |
Tfh | BCL6 | 0.234 | *** | 0.203 | *** |
IL21 | 0.127 | *** | 0.073 | * | |
Th17 | STAT3 | 0.357 | *** | 0.357 | *** |
IL17A | 0.068 | ** | 0.058 | 0.065 | |
Treg | FOXP3 | 0.195 | *** | 0.112 | *** |
CCR8 | 0.182 | *** | 0.139 | *** | |
STAT5B | -0.01 | 0.734 | -0.029 | 0.367 | |
Effector T-cell | TGFB1 | -0.005 | 0.866 | -0.12 | *** |
CX3CR1 | 0.008 | 0.789 | -0.063 | * | |
FGFBP2 | 0.222 | *** | 0.129 | *** | |
Naïve T-cell | FCGR3A | 0.185 | *** | 0.158 | *** |
CCR7 | 0.2 | *** | 0.093 | ** | |
SELL | 0.192 | *** | 0.086 | ** | |
TCF7 | 0.305 | *** | 0.225 | *** | |
Effective memory T-cell | LEF1 | 0.022 | 0.457 | -0.04 | 0.204 |
PDCD1 | 0.213 | *** | 0.117 | *** | |
DUSP4 | -0.087 | ** | -0.131 | *** | |
GZMK | 0.141 | *** | 0.013 | 0.688 | |
Resident memory T-cell | GZMA | 0.19 | *** | 0.085 | ** |
IFNG | 0.209 | *** | 0.15 | *** | |
CD69 | 0.2 | *** | 0.084 | ** | |
ITGAE | 0.015 | 0.62 | 0.044 | 0.17 | |
CXCR6 | 0.252 | *** | 0.159 | *** | |
Exhausted T-cell | MYADM | -0.067 | * | -0.069 | * |
HAVCR2 | 0.214 | *** | 0.166 | *** | |
TIGIT | 0.248 | *** | 0.159 | *** | |
LAG3 | 0.206 | *** | 0.163 | *** | |
PDCD1 | 0.213 | *** | 0.117 | *** | |
CXCL13 | 0.229 | *** | 0.16 | *** | |
Resting Treg T-cell | LAYN | 0.056 | 0.0642 | -0.041 | 0.199 |
FOXP3 | 0.195 | *** | 0.112 | *** | |
IL2RA | 0.288 | *** | 0.224 | *** | |
Effective Treg T-cell | FOXP3 | 0.195 | *** | 0.112 | *** |
CTLA4 | 0.247 | *** | 0.172 | *** | |
CCR8 | 0.182 | *** | 0.139 | *** | |
TNFRSF9 | 0.298 | *** | 0.227 | *** | |
Th1-like | CXCL13 | 0.229 | *** | 0.16 | *** |
HAVCR2 | 0.214 | *** | 0.166 | *** | |
IFNG | 0.209 | *** | 0.15 | *** | |
CXCR3 | 0.167 | *** | 0.055 | 0.0846 | |
BHLHE40 | -0.161 | *** | -0.15 | *** | |
CD4 | 0.22 | *** | 0.127 | *** | |
CCR7 | 0.2 | *** | 0.093 | ** | |
General memory T-cell | SELL | 0.192 | *** | 0.086 | ** |
IL7R | 0.261 | *** | 0.162 | *** |