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Overexpression of NLRC5 suppressed the production of inflammatory cytokines in IL-1β-stimulated human OA chondrocytes. After transfection with pcDNA3.1-NLRC5 or pcDNA3.1 vector and the following incubation with IL-1β, (A–D) the production of TNF-α, IL-6, MMP-3 and MMP-13 were detected using ELISA. *p < 0.05.
