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Knockdown of NLRC5 increased the production of inflammatory cytokines in IL-1β-stimulated human OA chondrocytes. After transfection with si-NLRC5/si-NC and the following incubation with IL-1β, (A–D) the production of TNF-α, IL-6, MMP-3 and MMP-13 were detected using ELISA. *p < 0.05.
