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NLRC5 inhibited IL-1β-induced NF-κB activation in chondrocytes. After transfection with pcDNA3.1-NLRC5 or pcDNA3.1 vector, the chondrocytes were stimulated by IL-1β (10 ng/ml) for 24 h. (A–C) The expression levels of p-p65, p65, IĸBα were determined using western blot analysis. *p < 0.05.
