Table 2. RUSC1-AS1 was an independent prognostic factor for osteosarcoma.

Variables	Patients (N)	Univariate Cox Analysis		Multivariate Cox Analysis
		HR (95% CI)	P value	HR (95% CI)	P value
Age (y)
≥18/<18	13/24	0.892 (0.691–1.415)	0.495
Gender
Male/Female	22/15	0.971 (0.433–2.591)	0.882
Stage
I-IIA/IIB-III	12/25	2.688 (1.412–6.691)	0.042
Size (cm)
<5/≥5	16/21	1.981 (0.781–5.233)	0.069
Metastasis
No/Yes	13/24	2.335 (1.203–6.216)	0.002	1.892 (1.023–5.135)	0.013
RUSC1-AS1
High/Low	18/19	2.913 (1.324–9.452)	0.001	2.541 (1.145–8.219)	0.022