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. 2021 Aug 19;13(16):20383–20394. doi: 10.18632/aging.203420

Figure 1.

Figure 1

Hsa_circ_0134111 knockdown prevents IL-1β-induced growth inhibition in chondrocytes. (A) Chondrocytes were treated with hsa_circ_0134111 siRNA-ctrl, hsa_circ_0134111 siRNA1, hsa_circ_0134111 siRNA2, or hsa_circ_0134111 siRNA3 and RT-qPCR was performed to measure knockdown efficiency. (B) Chondrocytes were treated with IL-1β and hsa_circ_0134111 siRNA1, alone or in combination, and RT-qPCR was performed to measure hsa_circ_0134111 levels in cells. (C) Results of the CCK-8 assay, used to detect cell viability. (D, E) EdU and DAPI staining was used to measure chondrocyte proliferation. **P<0.01 compared with control; ##P<0.01 compared with hsa_circ_0134111 siRNA1.