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. 2021 Aug 19;13(16):20383–20394. doi: 10.18632/aging.203420

Figure 6.

Figure 6

Hsa_circ_0134111 knockdown alleviates the symptoms of OA in vivo. Representative images of knee articular tissue stained with (A) H&E and (B) Safranin O/Fast Green. (C) Subchondral bone thickness measurements. (D) Synovitis scores for knee joints in the different experimental treatments. (E, F) ELISA-based measurements of IL-6 and TNF-α levels in knee synovia. (G) Representative IHC images showing the expression of CCL1 and CCR8 in knee joint tissue. (H) A graphical abstract of this study. **P<0.01, compared with control; ##P<0.01, compared with OA.