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. 2021 Aug 16;76(10):1775–1783. doi: 10.1093/gerona/glab208

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© The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Protective effects of recombinant human LAV-BPIFB4 against SARS-CoV-2 lysate-induced cytotoxicity in vitro. Bar graph showing average cytotoxicity (±SD) determined using LDH assay in (A) BEAS-2B (human bronchial epithelial cells), (B) A549 (human alveolar basal epithelial cells), and (C) HUVEC (human umbilical vein endothelial cells) following 3 days treatment with SARS CoV-2 lysate or control lysate (50 μg/mL) in presence or absence of rhLAV-BPIFB4 (18 ng/mL; n = 3). p-values indicate significance levels comparing average lactate dehydrogenase release among different groups (analysis of variance).