Table 1.
Characteristics of included patients over cohort years
| All years N = 514,2921 |
2011 N = 16,360 |
2012 N = 26,069 |
2013 N = 34,459 |
2014 N = 41,747 |
2015 N = 48,592 |
2016 N = 54,189 |
2017 N = 65,010 |
2018 N = 75,072 |
2019 N = 84,803 |
2020 N = 67,991 |
|
|---|---|---|---|---|---|---|---|---|---|---|---|
| Age, years, mean (SD) | 61 (20) | 64 (19) | 64 (19) | 63 (19) | 62 (20) | 62 (20) | 61 (20) | 61 (20) | 61 (20) | 61 (21) | 60 (20) |
| SAPS 3, points, mean (SD) | 42 (12) | 43 (13) | 42 (13) | 42 (12) | 42 (12) | 42 (13) | 42 (13) | 42 (13) | 42 (12) | 41 (12) | 40 (13) |
| CCI, points2, mean (SD) | 1.20 (1.77) | 1.36 (1.82) | 1.27 (1.74) | 1.26 (1.77) | 1.14 (1.67) | 1.15 (1.67) | 1.17 (1.68) | 1.19 (1.70) | 1.18 (1.7) | 1.20 (1.83) | 1.24 (1.98) |
| Performance impairment, n (%) | |||||||||||
| Absent/minor | 386,391 (75%) | 12,681 (78%) | 20,595 (79%) | 26,874 (78%) | 32,642 (78%) | 37,296 (77%) | 41,074 (76%) | 46,450 (71%) | 55,828 (74%) | 61,331 (72%) | 51,620 (76%) |
| Moderate | 94,962 (18%) | 2334 (14%) | 3604 (14%) | 5119 (15%) | 5867 (14%) | 8252 (17%) | 9951 (18%) | 14,619 (22%) | 14,389 (19%) | 18,065 (21%) | 12,762 (19%) |
| Severe | 32,939 (6.4%) | 1345 (8.2%) | 1870 (7.2%) | 2466 (7.2%) | 3238 (7.8%) | 3044 (6.3%) | 3164 (5.8%) | 3941 (6.1%) | 4855 (6.5%) | 5407 (6.4%) | 3609 (5.3%) |
| Admission type, n (%) | |||||||||||
| Elective surgery | 91,242 (18%) | 3,395 (21%) | 5,309 (20%) | 6,493 (19%) | 7,441 (18%) | 8,595 (18%) | 9,917 (18%) | 11,493 (18%) | 12,132 (16%) | 13,044 (15%) | 13,423 (20%) |
| Medical | 405,611 (79%) | 12,279 (75%) | 19,965 (77%) | 26,657 (77%) | 33,059 (79%) | 38,707 (80%) | 42,577 (79%) | 51,422 (79%) | 60,511 (81%) | 68,858 (81%) | 51,576 (76%) |
| Urgent surgery | 17,439 (3.4%) | 686 (4.2%) | 795 (3%) | 1309 (3.8%) | 1247 (3.0%) | 1290 (2.7%) | 1695 (3.1%) | 2095 (3.2%) | 2429 (3.2%) | 2901 (3.4%) | 2992 (4.4%) |
| Presence of infection3, n (%) | 103,039 (20%) | 2765 (17%) | 4699 (18%) | 6555 (19%) | 8214 (20%) | 10,746 (22%) | 11,784 (22%) | 13,090 (20%) | 15,293 (20%) | 17,458 (21%) | 12,435 (18%) |
| Mechanical ventilation at admission, n (%) | 20,336 (4%) | 1319 (8.1%) | 1671 (6.4%) | 1948 (5.7%) | 2178 (5.2%) | 2236 (4.6%) | 2135 (3.9%) | 2315 (3.6%) | 2125 (2.8%) | 2371 (2.8%) | 2038 (3%) |
| Vasopressor at admission, n (%) | 21,106 (4.1%) | 932 (5.7%) | 1286 (4.9%) | 1893 (5.5%) | 1910 (4.6%) | 2312 (4.8%) | 2206 (4.1%) | 2621 (4%) | 2526 (3.4%) | 3022 (3.6%) | 2398 (3.5%) |
| ICU length-of-stay (days), mean (SD) | 4.7 (9.6) | 4.7 (15.6) | 4.9 (17.4) | 4.8 (10.7) | 4.9 (11.2) | 4.9 (9.5) | 4.9 (9.1) | 4.8 (8.6) | 4.6 (8.2) | 4.4 (7.2) | 4.2 (7) |
| Hospital mortality, n (%) | 39,161 (7.6%) | 1847 (11%) | 2941 (11%) | 3583 (10%) | 4040 (9.7%) | 4332 (8.9%) | 4286 (7.9%) | 4448 (6.8%) | 4558 (6.1%) | 4768 (5.6%) | 4358 (6.4%) |
1Mean (SD); n (%)
2Charlson Comorbidity Index
3Presence of infection at enrollment. COVID-19 patients are not included in the table