Table 3.
Ventilatory Settings, Respiratory Mechanics, and Gas Exchange before ECMO Initiation
| Parameter | Total | Survivors | Nonsurvivors | P Value |
|---|---|---|---|---|
| VT (mL/kg PBW) | 5.4 (4.7–6.0) | 5.5 (4.6–6.0) | 5.0 (4.9–5.9) | 0.390 |
| PEEP, cm H2O | 10.4 (4.1) | 10.7 (4.1) | 9.8 (4.1) | 0.350 |
| Plateau pressure, cm H2O | 26.2 (5.2) | 25.5 (5.6) | 27.3 (4.3) | 0.120 |
| Driving pressure, cm H2O | 15.0 (14.0–18.0) | 15.0 (14.0–16.0) | 16.0 (15.0–20.0) | 0.008 |
| Static compliance, mL/cm H2O | 22.0 (18.0–28.0) | 23.5 (19.0–29.0) | 19.5 (14.5–24.0) | 0.002 |
| FiO2, % | 90 (70–100) | 80 (70–100) | 100 (80–100) | 0.043 |
| PaO2, mm Hg | 71.8 (18.3) | 70.8 (18.2) | 73.3 (18.7) | 0.550 |
| PaO2/FiO2 ratio | 86.8 (63.7–99.2) | 80 (64.0–98.3) | 87.8 (62.0–100.0) | 0.990 |
| PaCO2, mm Hg | 58.2 (46.7–71.0) | 58.0 (44.5–69.0) | 64.0 (55.0–82.0) | 0.066 |
| pH | 7.30 (0.1) | 7.31 (0.1) | 7.25 (0.1) | 0.009 |
Definition of abbreviations: ECMO = extracorporeal membrane oxygenation; IQR = interquartile range; PBW = predicted body weight; PEEP = positive end-expiratory pressure.
Data shown are the median (IQR) or mean (SD).