Table 2.
Laboratory Findings in COVID-19 Patients Characteristics Between Hypoalbuminemia and Normal Albumin Group
| Indicators | Total (n=482) | Albumin | P value | |
|---|---|---|---|---|
| ≥35 (223,42.3%) | <35 (259,53.7%) | |||
| Albumin, g/L | 34.15(30.6–38.0) | 38.3(36.6–39.7) | 30.8(28.5–32.9) | |
| CRP, mg/L | 16.1(3.5–51.3) | 4.6(0.8–14.5) | 42.3(0.5–9.1) | <0.001 |
| >10 | 268/461(58.1%) | 69/209(33.0%) | 199/252(79.0%) | <0.001 |
| WBC count, ×109 /L | 5.2(3.9–6.9) | 4.9(3.8–6.2) | 5.6(4.0–7.6) | <0.001 |
| <4 | 129/481(26.8%) | 65/222(29.3%) | 64/259(24.7%) | NA |
| 4–10 | 314/481(65.3%) | 156/222(70.3%) | 158/259(61.0%) | NA |
| >10 | 38/481(7.9%) | 1/222(0.5%) | 37/259(14.3%) | <0.001 |
| Platelet count, ×109 /L | 202(149–265) | 206(153.3–266.8) | 194.5(140.7–258.3) | 0.071 |
| Lymphocyte count, ×109 /L | 1.1(0.73–1.50) | 1.37(1.03–1.78) | 0.86(0.64–1.24) | <0.001 |
| <1.0 | 202/481(42.0%) | 48/222(21.6%) | 154/259(59.4%) | <0.001 |
| Eosinophil count, ×109 /L | 0.02(0–0.07) | 0.04(0.01–0.09) | 0.01(0–0.06) | <0.001 |
| <0.02 | 226/481(47.0%) | 72/222(32.4%) | 154/259(59.5%) | <0.001 |
| Creatinine, μmol/L | 68(57.0–83.7) | 66.1(57.4–79.8) | 70(56.3–86) | 0.074 |
| >133 | 15/479(3.1%) | 3/222(1.4%) | 12/257(4.7%) | 0.069 |
| ALT, U/L | 21(15–35) | 19(13.5–28) | 24(17–42.3) | <0.001 |
| >40 | 96/482(19.9%) | 25/223(11.2%) | 71/259(27.4%) | <0.001 |
| AST, U/L | 26(19–37) | 22(17–28.5) | 32(23–46) | <0.001 |
| >40 | 98/482(20.3%) | 17/223(7.6%) | 81/259(31.3%) | <0.001 |
| TBil, μmol/L | 9.1(6.6–12.6) | 8(6–10.4) | 10.4(7.6–13.6) | <0.001 |
| ALP, U/L | 64(53–79) | 62(52–75) | 66(52.7–84) | 0.013 |
| γ-GT, U/L | 26(16–48) | 21(14–36.5) | 30(19–62.3) | <0.001 |
| LDH, U/L | 244(193–331) | 206(177–253) | 307.5(235–437) | <0.001 |
| >245 | 223/450(49.6%) | 56/209(26.8%) | 167/238(70.2%) | <0.001 |
| CK, μmol/L | 70(48–133) | 50(3–81.5) | 90(51.5–164) | <0.001 |
| >185 | 42/262(16.0%) | 11/120(9.2%) | 31/142(21.8%) | 0.005 |
| PT, seconds | 13.4(12.7–14.2) | 13.3(12.8–14) | 13.6(12.3–14.4) | 0.156 |
| ≥16 | 24/458(5.2%) | 2/210(1.0%) | 22/248(8.9%) | <0.001 |
| APTT, seconds | 37.2(33.1–41.3) | 38(34.4–41.7) | 36.3(29.7–40.8) | 0.006 |
| D-dimer, μg/mL | 0.58(0.31–1.33) | 0.36(0.22–0.60) | 0.95(0.49–2.2) | <0.001 |
| ≥0.5 | 244/446(54.7%) | 66/204(32.4%) | 178/242(73.6%) | <0.001 |
| Hemoglobin, g/L | 129(118–138) | 129(120–140) | 128(116–137) | 0.105 |
| Globulin, g/L | 31(27.7–34.5) | 29.2(26.3–32.1) | 32.7(29.4–36.3) | <0.001 |
Abbreviations: COVID-19, coronavirus disease 2019; CRP, C-reactive protein; WBC, white blood cell; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBil, total bilirubin; ALP, alkaline phosphatase; γ-GT, γ-glutamyl transpeptidase; LDH, lactate dehydrogenase; CK, Creatine kinase; PT, Prothrombin time; APTT, activated partial thromboplastin time; NA, not available.