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. Author manuscript; available in PMC: 2021 Sep 13.
Published in final edited form as: J Thorac Oncol. 2020 Jan 28;15(5):843–859. doi: 10.1016/j.jtho.2020.01.012

Figure 4. BAP1 expression in different human cancer cell lines including BAP1-mutant does not correlate with sensitivity to the PARPIs talazoparib and olaparib.

Figure 4.

The graph created using CellMiner web application (http://discover.nci.nih.gov/cellminercdb) shows representing BAP1 expression (x-axis) and drug sensitivity (y-axis) in the GDSC (Genomics of Drug Sensitivity in Cancer). Colored dot represents single cell lines from the indicated tissues of origin. Pearson’s correlation coefficient (r) and two-sided P value between BAP1 transcript and the PARPIs talazoparib (A) and olaparib (C) are indicated. BAP1-mutant tissues also fail to show any correlation between BAP1 mutations and sensitivity to talazoparib (B) or olaparib (D).