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. 2021 Jun 15;105(2):413–420. doi: 10.4269/ajtmh.21-0299

Table 2.

Clinical presentation of coronavirus disease 2019 cases and severity outcome in Asia

Clinical symptoms Country Severity P value*
China (n = 30) Indonesia (n = 8) India (n = 33) Japan (n = 21) Malaysia (n = 19) Pakistan (n = 19) Singapore (n = 130) Mild/moderate (n = 230) Severe/critical (n = 26)
Asymptomatic 7 (30.4) 1 (25.0) 16 (57.1) 6 (37.5) 7 (36.8) 0 (0.0) 67 (58.8) 102 (52.6) 0 (0.0) 0.002
Fever 10 (33.3) 6 (75.0) 11 (33.3) 13 (61.9) 10 (52.6) 13 (68.4) 36 (27.7) 78 (33.9) 20 (76.9) < 0.001
Cough 15 (50.0) 7 (87.5) 6 (18.2) 3 (14.3) 4 (21.1) 5 (26.3) 20 (15.4) 49 (21.3) 11 (42.3) 0.017
Coryza 4 (13.3) 1 (12.5) 1 (3.0) 3 (14.3) 2 (10.5) 0 (0.0) 26 (20.0) 36 (15.7) 1 (3.8) 0.105
Sore throat 1 (3.3) 1 (12.5) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 13 (10.0) 15 (6.5) 0 (0.0) 0.180
Wheezing 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) NA
Crepitations 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 2 (10.5) 0 (0.0) 0 (0.0) 1 (3.8) 0.367
Headache 1 (3.3) 1 (12.5) 1 (3.0) 0 (0.0) 0 (0.0) 0 (0.0) 4 (3.1) 7 (3.0) 0 (0.0) 0.633
Irritability 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 2 (1.5) 2 (0.9) 0 (0.0) 0.008
Refuse feeding 0 (0.0) 2 (25.0) 0 (0.0) 0 (0.0) 1 (5.3) 1 (5.3) 0 (0.0) 2 (0.9) 2 (7.7) 0.001
Diarrhea 1 (3.3) 1 (12.5) 3 (9.1) 2 (9.5) 2 (10.5) 5 (26.3) 6 (4.6) 13 (5.7) 6 (23.1) < 0.001
Vomiting 0 (0.0) 0 (0.0) 3 (9.1) 3 (14.3) 0 (0.0) 5 (26.3) 3 (2.3) 5 (2.2) 9 (34.6) 0.001
Seizures 0 (0.0) 0 (0.0) 1 (3.0) 0 (0.0) 0 (0.0) 2 (10.5) 0 (0.0) 1 (0.4) 2 (7.7) < 0.001

NA = not applicable. Categorical variables are presented as count (percentage).

*

The P value shows the differences between the two severity groups.