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INF-γ-inducing peptide-based vaccines derived from CDC25B or COX2 inhibit the growth of MC38 in vivo. Mean (± SEM) tumor volume (mm3) in multi-peptide immunized mice (▪) or PBS immunized mice (●) for (A) CDC25B peptide mix, (B) COX2 peptide mix and (C) RCAS1 peptide mix. ****p < 0.0001, n = 4-8 mice/group.
