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. 2021 Aug 30;15:719076. doi: 10.3389/fnint.2021.719076

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Copyright © 2021 Rivera, Lindsay, Oliva, Bozinovic and Inestrosa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of the cognitive performance of young group (12-, and 24-months-old, n = 19) and aged group (38-, 56-, and 75-months-old, n = 20): short-term memory measured by (A) the Recognition Index (RI) of the Social Interaction test, (B) the RI of the novel local recognition test, and (C) the RI of the novel object recognition test. Long-term memory measured during the test phase of the Barnes maze: (D) latency to the first visit of the escape hole, (E) reference memory errors to find the escape hole (every first visit of a non-escape hole in each trial), and (F) working memory errors (repeated visits to the same non-escape hole in the same trial). The data were analyzed statistically by one-way ANOVA followed by Tukey's post hoc test.