Table 1.
Characteristics | Patients with haematologic malignancy (n = 25) | Patients without haematologic malignancy (n = 25) | p |
---|---|---|---|
Age (years)a | 64.8 ± 16.0 | 66.7 ± 11.1 | NS |
Male genderb | 19 (76) | 19 (76) | NS |
Haematologic cancerb | |||
- AML - ALL - DLBCL - Hodgkin lymphoma - Low-grade lymphoma - CLL - MM |
8 (32) 3 (12) 5 (20) 1 (4) 3 (12) 1 (4) 4 (16) |
||
Number of oncologic treatment linesb | |||
- 0 - 1 - 2 - 3 |
2 (8) 17 (68) 5 (20) 1 (4) |
||
Comorbiditiesb | |||
- Undernutrition - Hypertension - Cardiovascular disease - Dyslipidaemia - Diabetes - Currently smoking - Chronic lung disease - Chronic kidney failure |
16 (64) 10 (40) 8 (32) 7 (28) 5 (20) 5 (20) 4 (16) 1 (4) |
0 (0) 11 (44) 4 (16) 8 (32) 14 (56) 2 (8) 4 (16) 3 (12) |
< 0.001 NS NS NS 0.019 NS NS NS |
Symptomsb - Oxygen need - Fever - ARDS |
21 (84) 16 (64) 15 (60) 5 (20) |
25 (100) 25 (100) 18 (72) 1 (4) |
|
Minimal Cta | 17.2 ± 5.2 | 26.5 ± 5.1 | < 0.0001 |
Days of RT-PCR positivitya | 21.2 ± 15.9 | 7.4 ± 5.6 | < 0.01 |
Grade of lung involvementb | |||
- No lesion - Minimal - Moderate - Intermediate - Severe - Critical |
2 (10.5) 6 (31.6) 2 (10.5) 5 (26.3) 3 (15.8) 1 (5.3) |
0 (0) 1 (4) 12 (48) 10 (40) 2 (8) 0 (0) |
NS 0.032 0.01 NS NS NS |
COVID-19 managementb | |||
- Heparins - Antibiotics - AZT - Dexamethasone - Anakinra - Ruxolitinib - HCQ - Remdesivir |
19 (76) 20 (80) 10 (40) 9 (36) 7 (28) 4 (16) 3 (12) 2 (8) |
25 (100) 25 (100) 24 (96) 25 (100) 1 (4) 3 (12) 8 (32) 0 (0) |
0.022 NS < 0.0001 < 0.0001 0.049 NS NS NS |
Oxygen durationa | 11.2 ± 13.6 | 9.9 ± 4.9 | NS |
Mechanical ventilationb | 5 (20) | 1 (4) | NS |
ICU transferb | 9 (36) | 6 (24) | NS |
Deathb | 10 (40) | 1 (4) | < 0.001 |
amean ± standard deviation
bn (%)
NS, non-significant; AML, acute myeloid leukaemia; ALL, acute lymphoid leukaemia; DLBCL, diffuse large B cell lymphoma; CLL, chronic lymphoid leukaemia; MM, multiple myeloma; ARDS, acute respiratory distress syndrome; Ct, cycle threshold; AZT, azithromycin; HCQ, hydroxychloroquine; ICU, intensive care unit