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. 2021 Sep 13;100(11):2799–2803. doi: 10.1007/s00277-021-04656-z

Table 1.

Characteristics of the patients

Characteristics Patients with haematologic malignancy (n = 25) Patients without haematologic malignancy (n = 25) p
Age (years)a 64.8 ± 16.0 66.7 ± 11.1 NS
Male genderb 19 (76) 19 (76) NS
Haematologic cancerb

  - AML

  - ALL

  - DLBCL

  - Hodgkin lymphoma

  - Low-grade lymphoma

  - CLL

  - MM

8 (32)

3 (12)

5 (20)

1 (4)

3 (12)

1 (4)

4 (16)

Number of oncologic treatment linesb

  - 0

  - 1

  - 2

  - 3

2 (8)

17 (68)

5 (20)

1 (4)

Comorbiditiesb

  - Undernutrition

  - Hypertension

  - Cardiovascular disease

  - Dyslipidaemia

  - Diabetes

  - Currently smoking

  - Chronic lung disease

  - Chronic kidney failure

16 (64)

10 (40)

8 (32)

7 (28)

5 (20)

5 (20)

4 (16)

1 (4)

0 (0)

11 (44)

4 (16)

8 (32)

14 (56)

2 (8)

4 (16)

3 (12)

 < 0.001

NS

NS

NS

0.019

NS

NS

NS

Symptomsb

  - Oxygen need

  - Fever

  - ARDS

21 (84)

16 (64)

15 (60)

5 (20)

25 (100)

25 (100)

18 (72)

1 (4)

Minimal Cta 17.2 ± 5.2 26.5 ± 5.1  < 0.0001
Days of RT-PCR positivitya 21.2 ± 15.9 7.4 ± 5.6  < 0.01
Grade of lung involvementb

  - No lesion

  - Minimal

  - Moderate

  - Intermediate

  - Severe

  - Critical

2 (10.5)

6 (31.6)

2 (10.5)

5 (26.3)

3 (15.8)

1 (5.3)

0 (0)

1 (4)

12 (48)

10 (40)

2 (8)

0 (0)

NS

0.032

0.01

NS

NS

NS

COVID-19 managementb

  - Heparins

  - Antibiotics

  - AZT

  - Dexamethasone

  - Anakinra

  - Ruxolitinib

  - HCQ

  - Remdesivir

19 (76)

20 (80)

10 (40)

9 (36)

7 (28)

4 (16)

3 (12)

2 (8)

25 (100)

25 (100)

24 (96)

25 (100)

1 (4)

3 (12)

8 (32)

0 (0)

0.022

NS

 < 0.0001

 < 0.0001

0.049

NS

NS

NS

Oxygen durationa 11.2 ± 13.6 9.9 ± 4.9 NS
Mechanical ventilationb 5 (20) 1 (4) NS
ICU transferb 9 (36) 6 (24) NS
Deathb 10 (40) 1 (4)  < 0.001

amean ± standard deviation

bn (%)

NS, non-significant; AML, acute myeloid leukaemia; ALL, acute lymphoid leukaemia; DLBCL, diffuse large B cell lymphoma; CLL, chronic lymphoid leukaemia; MM, multiple myeloma; ARDS, acute respiratory distress syndrome; Ct, cycle threshold; AZT, azithromycin; HCQ, hydroxychloroquine; ICU, intensive care unit