TABLE 2: Univariable and multivariable analysis of demographic, clinical and echocardiographic variables associated with in-hospital mortality.
| Univariable analysis: | |||
|---|---|---|---|
| Variable | OR: | 95% CI: | P-value: |
| Demographics and risk factors: | |||
| Age (each 1 year): | 1.03 | 1.01 - 1.05 | 0.013* |
| Sex (male): | 1.41 | 0.72 - 2.75 | 0.312 |
| Hypertension: | 0.98 | 0.41 - 2.28 | 0.926 |
| Diabetes: | 1.58 | 0.79 - 3.17 | 0.194 |
| Heart failure: | 0.85 | 0.32 - 2.24 | 0.737 |
| Obesity: | 0.73 | 0.24 - 2.24 | 0.587 |
| Asthma: | 1.50 | 0.38 - 5.85 | 0.561 |
| Smoking: | 0.94 | 0.44 - 2.02 | 0.877 |
| COVID-19 symptoms at admission: | |||
| Fever: | 0.89 | 0.46 - 1.72 | 0.732 |
| Cough: | 1.09 | 0.51 - 2.33 | 0.823 |
| Dyspnea: | 4.39 | 1.45 - 13.29 | 0.009* |
| Diarrhea: | 0.80 | 0.11 - 1.13 | 0.080 |
| Abdominal pain: | 1.16 | 0.27 - 5.07 | 0.840 |
| Anosmia: | 0.35 | 0.10 - 1.28 | 0.112 |
| Taste loss: | 0.21 | 0.05 - 0.97 | 0.045* |
| Echo variables: | |||
| LVEF (%) | 0.94 | 0.92 - 0.98 | <0.001* |
| RV dysfunction (any) | 5.33 | 2.33 - 12.21 | <0.001* |
| LA diameter (mm) | 0.94 | 0.88 - 1.00 | 0.062 |
| RV fractional area change (%) | 0.96 | 0.93 - 0.99 | 0.049* |
| TAPSE (mm) | 0.83 | 0.74 - 0.93 | 0.001* |
| RV basal dimension (mm) | 1.10 | 1.03 - 1.18 | 0.004* |
| Septal E/E’ | 1.07 | 0.97 - 1.17 | 0.202 |
| Tricuspid velocity (m/s) | 2.60 | 0.68 - 9.92 | 0.161 |
| Multivariable analysis†: | |||
| Age (each 1 year): | 1.05 | 1.01 - 1.10 | 0.023* |
| LVEF (%): | 0.96 | 0.91 - 0.99 | 0.048* |
| TAPSE (mm) | 0.76 | 0.63 - 0.91 | 0.005* |
Abbreviations: LA: left atrium; LVEF: left ventricular ejection fraction; OR: odds-ratio; RV: right ventricle; TAPSE: tricuspid annular plane systolic excursion. *p<0.05. † Multivariable analysis adjusted for sex, hypertension, diabetes, heart failure, asthma, obesity, fever, cough.