Figure 6.

Immune infiltration analysis. (a)The proportion of immune cells in each HCC patient. Macrophages and T cells were the main immune cells in HCC patients. (b)There were 9 different immune cell expressions between the low ABCC5 expression group and high ABCC5 expression group, including B cell memory, T cell CD8, T cells CD4 memory resting, T cells Follicular helper, T cells regulatory (Tregs), Monocytes, Macrophages M0, Macrophage M2, Dendritic cells activated. In addition, B cell memory, T cells CD4 memory activated, T cells Follicular helper, T cells regulatory (Tregs), Macrophages M0, and macrophagic cells activated were up-regulated in the high ABCC5 expression group (P < 0.05). T cell CD8, Monocytes, Macrophages M2 were down-regulated in the high ABCC5 expression group (P < 0.05). (c-l)Correlation analysis was conducted between the expression of ABCC5 gene and immune cells, and it was found that ABCC5 gene was correlated with 10 kinds of immune cells (P < 0.05), among which the immune cells positively correlated with ABCC5 were: T cells follicular helper, macrophagic cells resting, Macrophages M0, Eosinophils, B cells memory. ABCC5 negatively related immune cells were: T cell CD8, NK cells resting, Monocytes, Mast cells resting, Macrophage M1 (P < 0.05). (m)The intersection of the immune cells obtained by the above two methods got 6 types of significant immune cell. They were: Macrophages M0, Monocytes, Dendritic cells resting, B cells memory, T cells CD8, T cells Follicular Helper