Table 1.
Sham | OVX | PE-25 | PE-100 | PE-400 | PE-1600 | |
---|---|---|---|---|---|---|
ALT (U/L) | 17.46 ± 1.27 | 24.70 ± 2.51 | 24.87 ± 1.99 | 23.76 ± 1.31 | 20.77 ± 0.98 | 22.01 ± 1.60 |
AST (U/L) | 76.48 ± 5.11 | 109.00 ± 16.84 | 99.76 ± 6.44 | 93.73 ± 6.51 | 80.73 ± 6.37 | 74.90 ± 5.29 |
Ca (mg/dL) | 4.95 ± 0.31 | 4.47 ± 0.40 | 5.28 ± 0.12 | 5.28 ± 0.14 | 5.73 ± 0.13## | 5.72 ± 0.12## |
P (mg/dL) | 4.06 ± 0.22 | 4.49 ± 0.56 | 4.37 ± 0.30 | 4.28 ± 0.32 | 4.91 ± 0.20 | 4.45 ± 0.25 |
FFA (μM) | 197.3 ± 14.96 | 346.7 ± 35.42∗ | 254.2 ± 33.97 | 247.7 ± 37.05 | 321.40 ± 37.74 | 173.7 ± 42.8## |
Insulin (ng/mL) | 0.92 ± 0.04 | 1.23 ± 0.03∗∗∗ | 1.00 ± 0.04## | 1.11 ± 0.05 | 1.03 ± 0.05## | 0.94 ± 0.04### |
Data are presented as the mean ± standard error of mean (SEM). Sham, sham operation; OVX, ovariectomy; PE-25, OVX + PE 25 mg/kg; PE-100, OVX + PE 100 mg/kg; PE-400, OVX + PE 400 mg/kg; PE-1600, OVX + PE 1600 mg/kg; FFA, free fatty acid; ALT, alanine aminotransferase; AST, aspartate aminotransferase. ∗p < 0.05 and ∗∗∗p < 0.001 vs. OVX group; ##p < 0.01 and ###p < 0.001vs. OVX group.