Table 2.
Outcomes in lopinavir/ritonavir and lopinavir/ritonavir + atorvastatin treatments.
| Variables | Lopinavir/Ritonavir (n = 20) |
Lopinavir/Ritonavir + Atorvastatin (n = 20) |
P-value |
|---|---|---|---|
| Primary outcome | |||
| Duration of hospitalization (day), Mean (SD) | 9.75 (2.29) | 7.95 (2.04) | 0.012* |
| Secondary outcomes | |||
| Need for interferon or immunoglobulin, N (%) | 4 (20) | 3 (15) | 0.500*** |
| Receipt of invasive mechanical ventilation, N (%) | 1 (5) | 0 | NS |
| O2Sat (%), Mean (SD) | |||
| • Day 1 | 91.50 (1.79) | 91.50 (2.16) | 0.580* |
| • Day 6 | 91.50 (5.31) | 93.45 (3.22) | 0.168* |
| P-value | 1.000** | 0.030** | |
| CRP (mg/L), Mean (SD) | |||
| • Day 1 | 43.50 (22.12) | 57.70 (19.94) | 0.040* |
| • Day 6 | 44.45 (29.47) | 22.90 (19.31) | 0.010* |
| P-value | 0.909** | < 0.0001** |
SD: Standard deviation; N: Number; O2Sat: O2 saturation; CRP: C-Reactive protein; ICU: intensive unit care; NS: No Significant.
*
Independent T-Test between two groups.
**
Paired T-Test between day 1 and day 6.
***
Chi-Square.