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. 2021 Aug 21;297(3):101106. doi: 10.1016/j.jbc.2021.101106

Figure 10.

Figure 10

Atherosclerosis lesion analysis in ApoE−/−mice after bone marrow transplant. Bone marrows obtained from ApoE−/− (EKO), APOE2, APOE3, and APOE4 mice were transplanted into irradiated ApoE−/− mice and the animals were fed Western diet for 8 weeks. A, representative images (scale bar = 200 μm) of atherosclerotic lesions in aortic roots of EKO, APOE2, APOE3, and APOE4 bone marrow recipients. B, morphometric data of lesion area in the aortic roots of 12 mice in each group were analyzed by one-way ANOVA with the Holm–Sidak post hoc analysis for comparisons between groups. ## indicates significant difference at p < 0.01 from the other groups. C, morphometric data of plaque area in the whole aorta from 12 mice in each group were analyzed for statistical significance similarly. ## indicates significant difference at p < 0.01 from the other groups. apoE, apolipoprotein E.