Figure 8.

Lymphocyte composition in the blood of APOE gene replacement mice. Flow cytometry was used to analyze the number of (A) naïve CD4⁺ lymphocytes; (B) CD4⁺ T central memory cells; (C) CD4⁺ T effector memory cells; (D) naïve CD8⁺ T lymphocytes; (E) CD8⁺ T central memory cells; and (F) CD4⁺ T effector memory cells in the blood of APOE2 (N = 7), APOE3 (N = 7), and APOE4 (N = 8) gene replacement mice. One-way ANOVA with Student–Newman–Keuls post hoc test was used to evaluate significant differences as indicated. apoE, apolipoprotein E.