Table 3.
Major adverse eventsa
| Patients (n = 345) | |
|---|---|
| Major AE within 3 months of surgery | |
| Yes | 71 (20.6%) |
| No | 274 (79.4%) |
| Major AEsb | |
| New focal neurological deficit | 44 (12.8%) |
| Intracranial hemorrhage | 7 (2.0%) |
| Surgical site infection | 5 (1.4%) |
| Cerebrospinal fluid leak | 4 (1.2%) |
| Hydrocephalus | 4 (1.2%) |
| CNS infection | 3 (0.9%) |
| Wound dehiscence | 3 (0.9%) |
| Cerebral infarct | 2 (0.6%) |
| Acute heart failure | 1 (0.3%) |
| Death | 1 (0.3%) |
| Electrolyte disorder | 1 (0.3%) |
| Pulmonary embolus | 1 (0.3%) |
| Status epilepticus | 1 (0.3%) |
| Venous sinus thrombosis | 1 (0.3%) |
aMajor AEs defined as new focal neurological deficit or AE grade 3a or higher according to the Clavien-Dindo Classification [6]
bSum of percentages is larger than total major AE rate as some patients experienced more than one of the major AEs listed
Abbreviations: CNS, central nervous system