Fig. 3.

Defining TIA1 BE and discovery of target mRNAs. A TIA1 binding efficiency (BE) of three previously known TIA1 mRNA targets: TP53, MECP2, and UBE3A in hESCs. The threshold for positive calling of TIA1 binding is above 0.58 (log₂ scale—red dashed line). B TIA1 binding efficiency of mRNAs encoding ribosomal proteins (R-Proteins), in comparison to all detected transcripts. *p < 0.05 (two-tailed student’s t-test). C comparison of our dataset with a previously published CLIP-seq dataset of TIA1 target mRNAs in HEK293 cells