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. 2021 Aug 19;48(9):6349–6361. doi: 10.1007/s11033-021-06634-0

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© The Author(s) 2021

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Fig. 4 — Functional analysis of RIP-seq dataset. A gene ontology analysis show enrichment of developmental processes associated genes as TIA1 target mRNAs in hESCs. B example of gene ontologies enriched in “development and differentiation” processes. Red underlines indicate processes related to development into tissues from diverse embryonic origins that are expressed in hESCs and bound by TIA1. C example of genes enriched in “nervous system development” with critical roles in neurodevelopment, ASD-associated (orange and pink), and syndromic-associate (red)